Compound Detail
CHEMBL4167617
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Basic Information
| ChEMBL ID | CHEMBL4167617 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | WKYDMXGSNDBXRD-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
352.4
MW (Da)
4.25
ALogP
6
HBA
2
HBD
80.9
PSA (Ų)
0.58
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.91
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Hepatocyte CHEMBL3140324 | IC50 | 4.91 | 4.91 | 12300.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Hepatocyte | IC50 | = | 12300.0 | nM | 4.91 | Inhibition of glucagon-mediated gluconeogenesis in mouse primary hepatocytes pre... | 29733999 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 29733999 | 10.1016/j.ejmech.2018.04.028 | Hepatocyte | 3 |
Data from ChEMBL 36 via Core Engine