Compound Detail
CHEMBL4174293
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Basic Information
| ChEMBL ID | CHEMBL4174293 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FYRLFBNPIPBHKZ-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
334.4
MW (Da)
4.55
ALogP
3
HBA
0
HBD
34.5
PSA (Ų)
0.70
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.01
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Fatty-acid amide hydrolase 1 CHEMBL3229 | IC50 | 5.01 | 5.01 | 9800.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Fatty-acid amide hydrolase 1 | IC50 | = | 9800.0 | nM | 5.01 | Inhibition of FAAH in rat brain microsomes assessed as reduction in enzyme-media... | 30108777 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 30108777 | 10.1039/C6MD00683C | ADMET | 2 |
| 30108777 | 10.1039/C6MD00683C | Fatty-acid amide hydrolase 1 | 1 |
Data from ChEMBL 36 via Core Engine