Compound Detail
CHEMBL419767
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL419767 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | COLBUQNTUDHMHF-UHFFFAOYSA-N |
1
Targets
3
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
443.3
MW (Da)
2.65
ALogP
4
HBA
1
HBD
67.6
PSA (Ų)
0.43
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 3 meas. best 9.15
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Androgen receptor CHEMBL3072 | Ki | 9.15 | 9.15 | 0.7 | 3 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Androgen receptor | Ki | = | 0.71 | nM | 9.15 | Inhibitory constant against rat prostate cytosol androgen receptor using [3H]mib... | 10966753 |
| Androgen receptor | Ki | = | 0.7079 | nM | 9.15 | Inhibition of [3H]mibolerone binding to cytosolic androgen receptor of rat ventr... | 15715462 |
| Androgen receptor | Ki | = | 0.71 | nM | 9.15 | Inhibition of rat prostate cytosolic androgen receptor | 15454212 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 10966753 | 10.1021/jm000163y | Androgen receptor | 1 |
| 15715462 | 10.1021/jm0495879 | Androgen receptor | 1 |
| 15454212 | 10.1016/j.bmcl.2004.08.031 | Androgen receptor | 1 |
Data from ChEMBL 36 via Core Engine