Compound Detail
CHEMBL4203901
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL4203901 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DFPUJJXWKDCNBL-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
163.2
MW (Da)
0.50
ALogP
3
HBA
3
HBD
63.3
PSA (Ų)
0.52
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 4.35
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Aminopeptidase N CHEMBL2590 | Ki | 4.35 | 4.35 | 45000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Aminopeptidase N | Ki | = | 45000.0 | nM | 4.35 | Inhibition of hog kidney APN using [3H]Tyr1-Leu5-enkephalin as substrate preincu... | 29630364 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 29630364 | 10.1021/acs.jmedchem.7b00782 | Aminopeptidase N | 1 |
Data from ChEMBL 36 via Core Engine