Compound Detail
CHEMBL423331
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL423331 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FKOZYIIIHDNKFQ-JTQLQIEISA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
404.2
MW (Da)
2.22
ALogP
4
HBA
2
HBD
61.8
PSA (Ų)
0.74
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.71
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| D(2) dopamine receptor CHEMBL339 | IC50 | 6.71 | 6.71 | 196.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| D(2) dopamine receptor | IC50 | = | 196.0 | nM | 6.71 | In vivo inhibitory activity against dopamine (D2) receptor in rat caudate-putame... | 14592497 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 14592497 | 10.1016/j.bmcl.2003.08.063 | D(2) dopamine receptor | 1 |
| 14592497 | 10.1016/j.bmcl.2003.08.063 | D(1A) dopamine receptor | 1 |
Data from ChEMBL 36 via Core Engine