Compound Detail
CHEMBL4248427
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Basic Information
| ChEMBL ID | CHEMBL4248427 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | HIELEDJWYDZOEX-SFYZADRCSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
261.4
MW (Da)
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 7.37
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Angiotensin-converting enzyme CHEMBL1808 | IC50 | 7.37 | 7.37 | 43.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Angiotensin-converting enzyme | IC50 | = | 43.0 | nM | 7.37 | Inhibition of human ACE using Hip-His-Leu-OH as substrate after 1 hr by fluorime... | 29039662 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 29039662 | 10.1021/acs.jmedchem.7b00718 | Angiotensin-converting enzyme | 1 |
Data from ChEMBL 36 via Core Engine