Compound Detail
CHEMBL426824
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
COc1ccccc1C1(C)CC(C)(C)N(C(C)=O)c2ccc(NC(=O)c3ccc(-c4ccccc4)cc3)cc21
Basic Information
| ChEMBL ID | CHEMBL426824 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | SJYQFXHAAASNOU-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
518.7
MW (Da)
7.46
ALogP
3
HBA
1
HBD
58.6
PSA (Ų)
0.30
QED
2
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.77
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Follicle-stimulating hormone receptor CHEMBL2024 | IC50 | 6.77 | 6.77 | 170.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Follicle-stimulating hormone receptor | IC50 | = | 170.0 | nM | 6.77 | In vitro inhibition of maximum response on CHO-K1 cells expressing human Follicl... | 15771412 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 15771412 | 10.1021/jm049676l | Follicle-stimulating hormone receptor | 1 |
Data from ChEMBL 36 via Core Engine