Compound Detail
CHEMBL4279505
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Basic Information
| ChEMBL ID | CHEMBL4279505 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | AKXQBDGTSLJNBK-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
298.7
MW (Da)
3.71
ALogP
3
HBA
2
HBD
66.9
PSA (Ų)
0.85
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.96
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Probable global transcription activator SNF2L2 CHEMBL2362979 | IC50 | 6.96 | 6.96 | 110.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Probable global transcription activator SNF2L2 | IC50 | = | 110.0 | nM | 6.96 | Inhibition of recombinant His10-tagged ZZ-HCV3C-BRM ATPase-SnAC (636 to 1331 res... | 30339381 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 30339381 | 10.1021/acs.jmedchem.8b01318 | Transcription activator BRG1 | 1 |
| 30339381 | 10.1021/acs.jmedchem.8b01318 | Probable global transcription activator SNF2L2 | 1 |
Data from ChEMBL 36 via Core Engine