Compound Detail
CHEMBL4283567
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL4283567 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ABILEPBVJUKRID-ONEGZZNKSA-N |
1
Targets
3
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
369.4
MW (Da)
2.08
ALogP
7
HBA
3
HBD
122.2
PSA (Ų)
0.54
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Kd 3 meas. best 5.47
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Connector enhancer of kinase suppressor of ras 1 CHEMBL4296242 | Kd | 5.47 | 5.47 | 3370.0 | 3 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Connector enhancer of kinase suppressor of ras 1 | Kd | = | 3370.0 | nM | 5.47 | Binding affinity to N-terminal GST tagged CNK PH domain (unknown origin) by SPR ... | - |
| Connector enhancer of kinase suppressor of ras 1 | Kd | = | 3370.0 | nM | 5.47 | Binding affinity to CNKSR1 PH-domain (unknown origin) by SPR spectroscopy | - |
| Connector enhancer of kinase suppressor of ras 1 | Kd | = | 3370.0 | nM | 5.47 | Binding affinity to N-terminal GST-tagged CNK PHD (unknown origin) by SPR assay | - |
Data from ChEMBL 36 via Core Engine