Compound Detail

CHEMBL4297101

CEFTOBIPROLE MEDOCARIL SODIUM

💊 Approved Drug

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💊 Approved Drug

Cc1oc(=O)oc1COC(=O)N1CC[C@@H](N2CC/C(=C\C3=C(C(=O)[O-])N4C(=O)[C@@H](NC(=O)/C(=N/O)c5nsc(N)n5)[C@H]4SC3)C2=O)C1.[Na+]

ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID	CHEMBL4297101
Name	CEFTOBIPROLE MEDOCARIL SODIUM
Phase	Approved
Structure Type	MOL
InChI Key	MFAWUGGPPMTWPU-INRVRKGJSA-M
Therapeutic	✓ Yes
Parent Compound	CHEMBL1652606
Active Moiety	CHEMBL520642

Known Names

BAL-5788 BAL-5788-001 BAL5788 BAL5788-001 Ceftobiprole medocaril Ceftobiprole medocaril sodium Ceftobiprole medocaril sodium salt RO 65-5788 RO-65-5788 RO-655788 Zevtera

Targets

Activities

Assay Types

PK Parameters

Publications

Known Names

Indications

Mechanisms

Molecular Properties

690.7

MW (Da)

-0.54

ALogP

HBA

HBD

264.3

PSA (Å²)

0.09

QED

Ro5 Violations

Rot. Bonds

Drug Information

Molecule Type	Small molecule
First Approval	2024
Availability	Discontinued
Chirality	Single Enantiomer

Routes of Administration

Parenteral

Flags

Prodrug

USAN Stem	-aril; cef-
USAN Year	2006

Extended Properties

Molecular Formula	C26H25N8NaO11S2
MW	712.65
Aromatic Rings	2
Heavy Atoms	47
NP-Likeness	-0.36

Mechanism of Action

Mechanism	Action Type	Target	Direct	Efficacy
Penicillin-binding protein 1 inhibitor	INHIBITOR	Penicillin-binding protein 1	✓	✓
Penicillin-binding protein 2 inhibitor	INHIBITOR	Penicillin-binding protein 2	✓	✓
Penicillin-binding protein inhibitor	INHIBITOR	Penicillin-binding protein	✓	✓
Penicillin-binding protein 4 inhibitor	INHIBITOR	Penicillin-binding protein 4	✓	✓
Penicillin-binding protein 3 inhibitor	INHIBITOR	Penicillin-binding protein 3	✓	✓
MecA inhibitor	INHIBITOR	MecA	✓	✓

Indications

Adenocarcinoma Bacteremia Skin Diseases, Bacterial Infections Neonatal Sepsis Pneumonia Skin Diseases Staphylococcal Infections Staphylococcal Skin Infections Meningitis Bacterial Infections

Data from ChEMBL 36 via Core Engine