Compound Detail
CHEMBL432127
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Basic Information
| ChEMBL ID | CHEMBL432127 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | HBNWXKBIDMJOED-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
480.6
MW (Da)
5.79
ALogP
6
HBA
2
HBD
102.3
PSA (Ų)
0.22
QED
1
Ro5 Violations
14
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.3
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Cysteinyl leukotriene receptor CHEMBL2094254 | IC50 | 5.3 | 5.3 | 5000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Cysteinyl leukotriene receptor | IC50 | = | 5000.0 | nM | 5.3 | In vitro inhibition of SRS-A-induced contractions in guinea pig ileum | 3027332 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 3027332 | 10.1021/jm00384a029 | Cavia porcellus | 2 |
| 3027332 | 10.1021/jm00384a029 | Cysteinyl leukotriene receptor | 1 |
Data from ChEMBL 36 via Core Engine