Compound Detail
CHEMBL434340
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL434340 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | XYEPWVPUXZZYMN-KCGFPETGSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
296.3
MW (Da)
-1.02
ALogP
9
HBA
4
HBD
135.9
PSA (Ų)
0.57
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 6.46
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| NON-PROTEIN TARGET CHEMBL3879801 | IC50 | 6.46 | 6.46 | 350.0 | 1 |
| Unchecked CHEMBL612545 | IC50 | 6.46 | 6.46 | 350.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| NON-PROTEIN TARGET | IC50 | = | 350.0 | nM | 6.46 | Inhibitory concentration against hepatitis C virus NS5B-mediated RNA synthesis i... | 15715486 |
| Unchecked | IC50 | = | 350.0 | nM | 6.46 | Inhibition of Hepatitis C virus NS5B RNA-dependent RNA polymerase | 22516671 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 15715486 | 10.1021/jm0495172 | Unchecked | 1 |
| 15715486 | 10.1021/jm0495172 | NON-PROTEIN TARGET | 1 |
| 22516671 | 10.1016/j.bmc.2012.03.049 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine