Compound Detail
CHEMBL438117
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL438117 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | QBPSLYUXTXAENH-CBPNBUAGSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
292.3
MW (Da)
-1.50
ALogP
10
HBA
4
HBD
163.3
PSA (Ų)
0.52
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 5.94
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Human gammaherpesvirus 8 CHEMBL612780 | IC50 | 5.94 | 5.53 | 1140.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Human gammaherpesvirus 8 | IC50 | = | 1140.0 | nM | 5.94 | Cytotoxicity against Kaposi's sarcoma-associated herpesvirus infected BC3 cells ... | 17402726 |
| Human gammaherpesvirus 8 | IC50 | = | 7610.0 | nM | 5.12 | Cytotoxicity against Kaposi's sarcoma-associated herpesvirus infected BC2 cells ... | 17402726 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 17402726 | 10.1021/jm070032y | Human gammaherpesvirus 8 | 4 |
| 17402726 | 10.1021/jm070032y | ADMET | 1 |
| 17402726 | 10.1021/jm070032y | BC-3 | 1 |
Data from ChEMBL 36 via Core Engine