Compound Detail
CHEMBL43844
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Basic Information
| ChEMBL ID | CHEMBL43844 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FBFWJVBMWUEICM-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
339.5
MW (Da)
3.34
ALogP
4
HBA
0
HBD
18.9
PSA (Ų)
0.72
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.62
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Dopamine receptor CHEMBL2093868 | IC50 | 6.62 | 6.62 | 240.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Dopamine receptor | IC50 | = | 240.0 | nM | 6.62 | In vitro inhibition of [3H]haloperidol (HPD) binding to dopamine (DA) receptor o... | 2899647 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 2899647 | 10.1021/jm00403a022 | Rattus norvegicus | 2 |
| 2899647 | 10.1021/jm00403a022 | Dopamine receptor | 1 |
Data from ChEMBL 36 via Core Engine