Compound Detail
CHEMBL4439230
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Basic Information
| ChEMBL ID | CHEMBL4439230 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DRJFIETWWYIKKX-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
328.1
MW (Da)
2.63
ALogP
3
HBA
0
HBD
43.4
PSA (Ų)
0.74
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.12
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Trypanosoma cruzi CHEMBL368 | IC50 | 5.12 | 5.12 | 7570.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Trypanosoma cruzi | IC50 | = | 7570.0 | nM | 5.12 | Trypanocidal activity against Trypanosoma cruzi Y strain bloodstream trypomastig... | 31306817 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 31306817 | 10.1016/j.ejmech.2019.06.056 | Trypanosoma cruzi | 1 |
Data from ChEMBL 36 via Core Engine