Compound Detail
CHEMBL4463994
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL4463994 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DKTLTRFWOBFVSJ-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
331.5
MW (Da)
3.38
ALogP
4
HBA
3
HBD
70.2
PSA (Ų)
0.69
QED
0
Ro5 Violations
8
Rot. Bonds
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.46
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Interleukin-5 receptor subunit alpha CHEMBL4523198 | IC50 | 5.46 | 5.46 | 3500.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Interleukin-5 receptor subunit alpha | IC50 | = | 3500.0 | nM | 5.46 | Inhibition of IL-5 receptor in mouse pro-B Y16 cells assessed as decrease in mIL... | 31400705 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 31400705 | 10.1016/j.ejmech.2019.111574 | Interleukin-5 receptor subunit alpha | 2 |
| 31400705 | 10.1016/j.ejmech.2019.111574 | Unchecked | 2 |
Data from ChEMBL 36 via Core Engine