Compound Detail
CHEMBL4467793
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Basic Information
| ChEMBL ID | CHEMBL4467793 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | KTUFZHVVJBHGKZ-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
159.2
MW (Da)
2.29
ALogP
1
HBA
1
HBD
32.9
PSA (Ų)
0.64
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 6.8
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Transcription intermediary factor 1-alpha CHEMBL3108638 | IC50 | 6.8 | 6.8 | 156.6 | 1 |
| E3 ubiquitin-protein ligase TRIM33 CHEMBL2176772 | IC50 | 6.62 | 6.62 | 240.3 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Transcription intermediary factor 1-alpha | IC50 | = | 156.6 | nM | 6.8 | Inhibition of recombinant TRIM24 (unknown origin) using biotinylated H3 peptide ... | - |
| E3 ubiquitin-protein ligase TRIM33 | IC50 | = | 240.3 | nM | 6.62 | Inhibition of recombinant TRIM33 PHD bromodomain (unknown origin) using biotinyl... | - |
Data from ChEMBL 36 via Core Engine