Compound Detail
CHEMBL448798
CYMOPOL Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL448798 |
| Name | CYMOPOL |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | IUFDABCKTYWJDR-KPKJPENVSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
325.2
MW (Da)
5.10
ALogP
2
HBA
2
HBD
40.5
PSA (Ų)
0.58
QED
1
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.4
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| HL-60 CHEMBL383 | IC50 | 5.4 | 5.4 | 4000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| HL-60 | IC50 | = | 4000.0 | nM | 5.4 | Antioxidant activity against TPA-induced ROS production in human HL60 cells by 2... | 12762791 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 2691635 | 10.1021/np50065a028 | Salmonella typhimurium | 2 |
| 1479376 | 10.1021/np50089a002 | Salmonella typhimurium | 2 |
| 12762791 | 10.1021/np0204038 | HL-60 | 1 |
| 12762791 | 10.1021/np0204038 | Radical scavenging activity | 1 |
Data from ChEMBL 36 via Core Engine