Compound Detail
CHEMBL452406
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL452406 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | IFDHYEGUTZWRTK-UHFFFAOYSA-N |
3
Targets
4
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
258.7
MW (Da)
2.99
ALogP
4
HBA
1
HBD
42.2
PSA (Ų)
0.73
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 4 meas. best 5.96
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Small conductance calcium-activated potassium channel protein 3 CHEMBL3381 | IC50 | 5.96 | 5.88 | 1100.0 | 2 |
| Small conductance calcium-activated potassium channel protein 2 CHEMBL4469 | IC50 | 5.96 | 5.96 | 1100.0 | 1 |
| Small conductance calcium-activated potassium channel protein 1 CHEMBL2369 | IC50 | 5.92 | 5.92 | 1190.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 18824351 | 10.1016/j.bmcl.2008.08.026 | Small conductance calcium-activated potassium channel protein 3 | 3 |
| 18824351 | 10.1016/j.bmcl.2008.08.026 | Small conductance calcium-activated potassium channel protein 1 | 1 |
| 18824351 | 10.1016/j.bmcl.2008.08.026 | Small conductance calcium-activated potassium channel protein 2 | 1 |
Data from ChEMBL 36 via Core Engine