Compound Detail
CHEMBL4544160
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Basic Information
| ChEMBL ID | CHEMBL4544160 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | PMIDISUGGRZXRK-VQHVLOKHSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
308.3
MW (Da)
3.88
ALogP
4
HBA
0
HBD
44.8
PSA (Ų)
0.46
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 4.72
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Trypanosoma cruzi CHEMBL368 | EC50 | 4.72 | 4.72 | 18900.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Trypanosoma cruzi | EC50 | = | 18900.0 | nM | 4.72 | Antitrypanosomal activity against Trypanosoma cruzi Y trypomastigotes infected i... | 31000155 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 31000155 | 10.1016/j.bmcl.2019.04.020 | Trypanosoma cruzi | 1 |
| 31000155 | 10.1016/j.bmcl.2019.04.020 | L929 | 1 |
| 31000155 | 10.1016/j.bmcl.2019.04.020 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine