Compound Detail
CHEMBL4548728
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL4548728 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | QABLDFZIZKEHJZ-UHFFFAOYSA-N |
3
Targets
3
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
331.4
MW (Da)
5.07
ALogP
4
HBA
2
HBD
49.6
PSA (Ų)
0.54
QED
1
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 3 meas. best 6.79
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Sal-like protein 4 CHEMBL6067463 | IC50 | 6.79 | 6.79 | 162.0 | 1 |
| E3 ubiquitin-protein ligase TRIM33 CHEMBL2176772 | IC50 | 5.13 | 5.13 | 7451.0 | 1 |
| Transcription intermediary factor 1-alpha CHEMBL3108638 | IC50 | 5.11 | 5.11 | 7763.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Sal-like protein 4 | IC50 | = | 162.0 | nM | 6.79 | TBD: TBD | - |
| E3 ubiquitin-protein ligase TRIM33 | IC50 | = | 7451.0 | nM | 5.13 | Inhibition of recombinant TRIM33 PHD bromodomain (unknown origin) using biotinyl... | - |
| Transcription intermediary factor 1-alpha | IC50 | = | 7763.0 | nM | 5.11 | Inhibition of recombinant TRIM24 (unknown origin) using biotinylated H3 peptide ... | - |
Data from ChEMBL 36 via Core Engine