Compound Detail
CHEMBL4576579
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CC(C)C[C@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CCCCCCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O
Basic Information
| ChEMBL ID | CHEMBL4576579 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | GHLFIGVGFVELAS-CWANVFDFSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
1505.8
MW (Da)
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 6.26
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Neuropeptide Y receptor type 5 CHEMBL4561 | Ki | 6.26 | 6.26 | 550.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Neuropeptide Y receptor type 5 | Ki | = | 550.0 | nM | 6.26 | Displacement of [3H]propionyl-pNPY from human NPY Y5 receptor expressed in human... | 27223253 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 27223253 | 10.1021/acs.jmedchem.6b00309 | Neuropeptide Y receptor type 4 | 3 |
| 27223253 | 10.1021/acs.jmedchem.6b00309 | Neuropeptide Y receptor type 1 | 1 |
| 27223253 | 10.1021/acs.jmedchem.6b00309 | Neuropeptide Y receptor type 2 | 1 |
| 27223253 | 10.1021/acs.jmedchem.6b00309 | Neuropeptide Y receptor type 5 | 1 |
Data from ChEMBL 36 via Core Engine