Compound Detail
CHEMBL458091
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Basic Information
| ChEMBL ID | CHEMBL458091 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | VICCNECLQCWWKK-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
336.8
MW (Da)
4.93
ALogP
2
HBA
3
HBD
65.1
PSA (Ų)
0.49
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.05
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glycogen phosphorylase, liver form CHEMBL2568 | IC50 | 6.05 | 6.05 | 900.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glycogen phosphorylase, liver form | IC50 | = | 900.0 | nM | 6.05 | Inhibition of active form of human liver glycogen phosphorylase | 18952447 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 18952447 | 10.1016/j.bmc.2008.10.021 | Glycogen phosphorylase, liver form | 1 |
Data from ChEMBL 36 via Core Engine