Compound Detail
CHEMBL4583846
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL4583846 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | NBUAVJSFZXZRLL-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
393.4
MW (Da)
2.80
ALogP
6
HBA
1
HBD
82.5
PSA (Ų)
0.67
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 5.1
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| fMet-Leu-Phe receptor CHEMBL3359 | EC50 | 5.1 | 5.1 | 7943.3 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| fMet-Leu-Phe receptor | EC50 | = | 7943.28 | nM | 5.1 | Biased agonist activity at human FPR1 expressed in FlpIn-CHO cells assessed as s... | 31038950 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 31038950 | 10.1021/acs.jmedchem.8b01912 | fMet-Leu-Phe receptor | 2 |
| 31038950 | 10.1021/acs.jmedchem.8b01912 | N-formyl peptide receptor 2 | 2 |
Data from ChEMBL 36 via Core Engine