Compound Detail
CHEMBL458592
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Basic Information
| ChEMBL ID | CHEMBL458592 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | NFPYAWXXOSFWEX-CVEARBPZSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
364.4
MW (Da)
1.98
ALogP
5
HBA
3
HBD
104.7
PSA (Ų)
0.24
QED
0
Ro5 Violations
11
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.08
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Baculoviral IAP repeat-containing protein 2 CHEMBL5462 | IC50 | 6.08 | 6.08 | 840.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Baculoviral IAP repeat-containing protein 2 | IC50 | = | 840.0 | nM | 6.08 | Promotion of flag-tagged cIAP1 degradation in human HT1080 cells assessed as dec... | 18313309 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 18313309 | 10.1016/j.bmc.2008.02.024 | Baculoviral IAP repeat-containing protein 2 | 1 |
Data from ChEMBL 36 via Core Engine