Compound Detail
CHEMBL461952
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL461952 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | QQNYXAGTHKTAIZ-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
381.8
MW (Da)
4.25
ALogP
4
HBA
2
HBD
80.3
PSA (Ų)
0.69
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 8.05
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Macrophage colony-stimulating factor 1 receptor CHEMBL1844 | IC50 | 8.05 | 8.05 | 9.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Macrophage colony-stimulating factor 1 receptor | IC50 | = | 9.0 | nM | 8.05 | Inhibition of CSF1R | 18694641 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 18694641 | 10.1016/j.bmcl.2008.07.093 | Macrophage colony-stimulating factor 1 receptor | 1 |
| 18694641 | 10.1016/j.bmcl.2008.07.093 | NIH3T3 | 1 |
Data from ChEMBL 36 via Core Engine