Compound Detail
CHEMBL463453
DIHYDROMORIN Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL463453 |
| Name | DIHYDROMORIN |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | QIWOFDHUQPJCJF-LSDHHAIUSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
6
Publications
0
Known Names
Molecular Properties
304.2
MW (Da)
1.19
ALogP
7
HBA
5
HBD
127.5
PSA (Ų)
0.54
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.17
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Prostaglandin G/H synthase 1 CHEMBL221 | IC50 | 4.17 | 4.17 | 67100.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Prostaglandin G/H synthase 1 | IC50 | = | 67100.0 | nM | 4.17 | Inhibition of COX1 | 11858749 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 11678652 | 10.1021/np010288l | Aromatase | 1 |
| 11858749 | 10.1021/np010451c | Prostaglandin G/H synthase 1 | 1 |
| 11858749 | 10.1021/np010451c | Unchecked | 1 |
| 11858749 | 10.1021/np010451c | Prostaglandin G/H synthase 2 | 1 |
| 26481151 | 10.1016/j.bmc.2015.09.042 | RAW264.7 | 1 |
| 26481151 | 10.1016/j.bmc.2015.09.042 | No relevant target | 1 |
Data from ChEMBL 36 via Core Engine