Compound Detail
CHEMBL4635259
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Basic Information
| ChEMBL ID | CHEMBL4635259 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | YAXFAQRHDWWWJE-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
399.6
MW (Da)
4.63
ALogP
5
HBA
0
HBD
19.4
PSA (Ų)
0.59
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 2 meas. best 5.41
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Human orthopneumovirus CHEMBL613127 | EC50 | 5.41 | 5.245 | 3900.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Human orthopneumovirus | EC50 | = | 3900.0 | nM | 5.41 | Antiviral activity against Respiratory syncytial virus B infected in Hep2 cells ... | 32143992 |
| Human orthopneumovirus | EC50 | = | 8300.0 | nM | 5.08 | Antiviral activity against Respiratory syncytial virus A strain Long infected in... | 32143992 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 32143992 | 10.1016/j.bmc.2020.115401 | Human orthopneumovirus | 2 |
| 32143992 | 10.1016/j.bmc.2020.115401 | HEp-2 | 1 |
Data from ChEMBL 36 via Core Engine