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Compound Detail

CHEMBL464570

OREGONIN
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O=C(CCc1ccc(O)c(O)c1)C[C@H](CCc1ccc(O)c(O)c1)O[C@@H]1OC[C@@H](O)[C@H](O)[C@H]1O

Basic Information

ChEMBL ID CHEMBL464570
Name OREGONIN
Phase Preclinical
Structure Type MOL
InChI Key AQRNEKDRSXYJIN-IRFILORWSA-N
2
Targets
5
Activities
1
Assay Types
0
PK Parameters
15
Publications
0
Known Names

Molecular Properties

478.5
MW (Da)
0.86
ALogP
10
HBA
7
HBD
177.1
PSA (Ų)
0.24
QED
1
Ro5 Violations
10
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C24H30O10
MW 478.49
Aromatic Rings 2
Heavy Atoms 34
NP-Likeness 1.60

Activity Summary

IC50 5 meas. best 5.08

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
No relevant target
CHEMBL2362975
IC50 5.08 4.785 8400.0 2
RAW264.7
CHEMBL612557
IC50 5.01 4.8433 9700.0 3

Activity Data Samples

Top measurements by pChEMBL value

Literature References

Data from ChEMBL 36 via Core Engine