Compound Detail
CHEMBL4746238
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL4746238 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | IQJMHCGWAQPALZ-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
200.3
MW (Da)
1.99
ALogP
4
HBA
1
HBD
50.4
PSA (Ų)
0.81
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 4.3
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Tyrosinase CHEMBL1973 | Ki | 4.3 | 4.3 | 50000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Tyrosinase | Ki | = | 50000.0 | nM | 4.3 | Inhibition of human tyrosinase using L- DOPA as substrate by MBTH based assay | 32787103 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 32787103 | 10.1021/acs.jmedchem.0c00994 | Tyrosinase | 1 |
Data from ChEMBL 36 via Core Engine