Compound Detail
CHEMBL4752948
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Basic Information
| ChEMBL ID | CHEMBL4752948 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | MHQSGZLERONLEJ-NRFANRHFSA-N |
1
Targets
1
Activities
1
Assay Types
2
PK Parameters
2
Publications
0
Known Names
Molecular Properties
478.6
MW (Da)
4.05
ALogP
7
HBA
0
HBD
66.2
PSA (Ų)
0.53
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 7.77
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Fusion glycoprotein F0 CHEMBL3856166 | EC50 | 7.77 | 7.77 | 17.0 | 1 |
Pharmacokinetic Data
| Parameter | Value | Units | Species |
|---|---|---|---|
| T1/2 | 0.082 | hr | - |
| T1/2 | 0.105 | hr | - |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Fusion glycoprotein F0 | EC50 | = | 17.0 | nM | 7.77 | Inhibition of F protein in Respiratory syncytial virus A2 infected in HepG2 cell... | 33190073 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 33190073 | 10.1016/j.bmc.2020.115818 | No relevant target | 2 |
| 33190073 | 10.1016/j.bmc.2020.115818 | Fusion glycoprotein F0 | 1 |
Data from ChEMBL 36 via Core Engine