Compound Detail
CHEMBL4758615
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
CNC1CN(c2cc3n4nc(cc4n2)[C@@H]2CCCCN2C(=O)c2cc(F)ccc2OCC(=O)NCCN3C)C1
Basic Information
| ChEMBL ID | CHEMBL4758615 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DMHNHBINQSBFDO-NRFANRHFSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
536.6
MW (Da)
1.59
ALogP
9
HBA
2
HBD
107.3
PSA (Ų)
0.51
QED
1
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 8.15
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Fusion glycoprotein F0 CHEMBL3856166 | EC50 | 8.15 | 8.15 | 7.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Fusion glycoprotein F0 | EC50 | = | 7.0 | nM | 8.15 | Inhibition of F protein in Respiratory syncytial virus A2 infected in HepG2 cell... | 33190073 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 33190073 | 10.1016/j.bmc.2020.115818 | Fusion glycoprotein F0 | 1 |
| 33190073 | 10.1016/j.bmc.2020.115818 | ADMET | 1 |
Data from ChEMBL 36 via Core Engine