Compound Detail
CHEMBL4760869
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Basic Information
| ChEMBL ID | CHEMBL4760869 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | WUYPMJJFXQNSHK-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
412.4
MW (Da)
4.62
ALogP
4
HBA
3
HBD
96.1
PSA (Ų)
0.40
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.2
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Fibroblast growth factor receptor 4 CHEMBL3973 | IC50 | 6.2 | 6.2 | 632.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Fibroblast growth factor receptor 4 | IC50 | = | 632.0 | nM | 6.2 | Inhibition of FGFR4 (unknown origin) | 33618175 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 33618175 | 10.1016/j.ejmech.2021.113219 | Fibroblast growth factor receptor 1 | 1 |
| 33618175 | 10.1016/j.ejmech.2021.113219 | Fibroblast growth factor receptor 4 | 1 |
Data from ChEMBL 36 via Core Engine