Compound Detail
CHEMBL480663
CARYACHINE Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL480663 |
| Name | CARYACHINE |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | TZJNFQHUSMXCIT-GJZGRUSLSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
325.4
MW (Da)
2.96
ALogP
5
HBA
1
HBD
51.2
PSA (Ų)
0.87
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 5.05
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 1A CHEMBL214 | EC50 | 5.05 | 5.05 | 9000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 1A | EC50 | = | 9000.0 | nM | 5.05 | Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in... | 16562853 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 16562853 | 10.1021/np058114h | 5-hydroxytryptamine receptor 1A | 2 |
Data from ChEMBL 36 via Core Engine