Compound Detail
CHEMBL485021
3'-HYDROXYFLAVANONE Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL485021 |
| Name | 3'-HYDROXYFLAVANONE |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | JVSPTYZZNUXJHN-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
5
Publications
0
Known Names
Molecular Properties
240.3
MW (Da)
3.10
ALogP
3
HBA
1
HBD
46.5
PSA (Ų)
0.83
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.83
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Acetylcholinesterase CHEMBL3199 | IC50 | 6.83 | 6.83 | 147.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Acetylcholinesterase | IC50 | = | 147.0 | nM | 6.83 | Inhibition of AchE in Rattus norvegicus (rat) cortex homogenates by Ellman's met... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 19236029 | 10.1021/np800698d | Enterococcus faecalis | 2 |
| 19307119 | 10.1016/j.bmcl.2009.03.017 | HEK293 | 1 |
| 19307119 | 10.1016/j.bmcl.2009.03.017 | HeLa | 1 |
| 19236029 | 10.1021/np800698d | Unchecked | 1 |
| - | 10.1007/s00044-012-0162-3 | Acetylcholinesterase | 1 |
Data from ChEMBL 36 via Core Engine