Compound Detail
CHEMBL4853737
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Basic Information
| ChEMBL ID | CHEMBL4853737 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | AIGDWPMUHAMSCH-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
372.4
MW (Da)
2.17
ALogP
6
HBA
0
HBD
66.6
PSA (Ų)
0.55
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 4.85
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Cryptosporidium parvum CHEMBL612855 | EC50 | 4.85 | 4.85 | 14000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Cryptosporidium parvum | EC50 | = | 14000.0 | nM | 4.85 | Anti-cryptosporidial activity against Cryptosporidium parvum infected in HCT-8 c... | 34342443 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 34342443 | 10.1021/acs.jmedchem.1c01136 | Cryptosporidium parvum | 1 |
Data from ChEMBL 36 via Core Engine