Compound Detail
CHEMBL4865925
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL4865925 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | MENBIJGEZVUECC-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
510.4
MW (Da)
7.38
ALogP
5
HBA
1
HBD
81.8
PSA (Ų)
0.25
QED
2
Ro5 Violations
9
Rot. Bonds
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 6.58
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Bile acid receptor CHEMBL2047 | EC50 | 6.58 | 6.58 | 265.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Bile acid receptor | EC50 | = | 265.0 | nM | 6.58 | Agonist activity at FXR-LBD (unknown origin) assessed by ligand binding ability ... | 33360559 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 33360559 | 10.1016/j.ejmech.2020.113106 | Mus musculus | 6 |
| 33360559 | 10.1016/j.ejmech.2020.113106 | Bile acid receptor | 2 |
Data from ChEMBL 36 via Core Engine