Compound Detail
CHEMBL507082
CRIBRONIC ACID Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL507082 |
| Name | CRIBRONIC ACID |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | VGWGHJSLZPTLLA-VPENINKCSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
241.2
MW (Da)
-2.02
ALogP
6
HBA
4
HBD
133.2
PSA (Ų)
0.42
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 7.08
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glutamate NMDA receptor CHEMBL1907608 | IC50 | 7.08 | 7.08 | 83.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glutamate NMDA receptor | IC50 | = | 83.0 | nM | 7.08 | Displacement of [3H]CGP39653 from NMDA receptor in Sprague-Dawley rat brain memb... | 12828462 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 12828462 | 10.1021/np020590+ | Mus musculus | 4 |
| 12828462 | 10.1021/np020590+ | Glutamate NMDA receptor | 3 |
Data from ChEMBL 36 via Core Engine