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Compound Detail

CHEMBL5074637

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COc1ccc(Cc2cccc(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c2)cc1

Basic Information

ChEMBL ID CHEMBL5074637
Phase Preclinical
Structure Type MOL
InChI Key UUJGQDYRNYTUFA-OUUBHVDSSA-N
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
8
Publications
0
Known Names

Molecular Properties

376.4
MW (Da)
0.46
ALogP
7
HBA
4
HBD
108.6
PSA (Ų)
0.58
QED
0
Ro5 Violations
6
Rot. Bonds

Drug Information

Molecule Type Unknown
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C20H24O7
MW 376.41
Aromatic Rings 2
Heavy Atoms 27
NP-Likeness 1.11

Activity Summary

EC50 2 meas. best 4.9

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
C2C12
CHEMBL612655
EC50 4.9 4.83 12700.0 2

Activity Data Samples

Top measurements by pChEMBL value

Literature References

Data from ChEMBL 36 via Core Engine