Compound Detail
CHEMBL509170
ILLUDIN Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL509170 |
| Name | ILLUDIN |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DDLLIYKVDWPHJI-RDBSUJKOSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
264.3
MW (Da)
0.72
ALogP
4
HBA
3
HBD
77.8
PSA (Ų)
0.65
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 8.52
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| HL-60 CHEMBL383 | IC50 | 8.52 | 8.52 | 3.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| HL-60 | IC50 | = | 3.0 | nM | 8.52 | Cytotoxicity against human HL60 cells after 48 hrs by trypan blue exclusion assa... | 12608875 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 14510611 | 10.1021/np030205w | ADMET | 13 |
| 14510611 | 10.1021/np030205w | Human alphaherpesvirus 1 | 11 |
| 9051915 | 10.1021/np960596x | P388 | 1 |
| 12608875 | 10.1021/np0204085 | HL-60 | 1 |
Data from ChEMBL 36 via Core Engine