Compound Detail
CHEMBL509255
DISCORHABDIN V Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL509255 |
| Name | DISCORHABDIN V |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | SSPPRUOFJZYGKW-UHFFFAOYSA-O |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
387.3
MW (Da)
1.23
ALogP
3
HBA
3
HBD
68.1
PSA (Ų)
0.59
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.9
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| HCT-116 CHEMBL394 | IC50 | 5.9 | 5.9 | 1266.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| HCT-116 | IC50 | = | 1266.0 | nM | 5.9 | Cytotoxicity against human HCT116 cells after 72 hrs by MTS assay | 15332840 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 15332840 | 10.1021/np034084b | HCT-116 | 1 |
Data from ChEMBL 36 via Core Engine