Compound Detail
CHEMBL513588
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Basic Information
| ChEMBL ID | CHEMBL513588 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | KUHJNLPHCHGERT-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
424.3
MW (Da)
5.40
ALogP
4
HBA
2
HBD
71.1
PSA (Ų)
0.59
QED
1
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 7.96
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Macrophage colony-stimulating factor 1 receptor CHEMBL1844 | IC50 | 7.96 | 7.96 | 11.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Macrophage colony-stimulating factor 1 receptor | IC50 | = | 11.0 | nM | 7.96 | Inhibition of CSF1R | 18694641 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 18694641 | 10.1016/j.bmcl.2008.07.093 | Macrophage colony-stimulating factor 1 receptor | 1 |
| 18694641 | 10.1016/j.bmcl.2008.07.093 | NIH3T3 | 1 |
| - | 10.6019/CHEMBL3301361 | ADMET | 1 |
Data from ChEMBL 36 via Core Engine