Compound Detail
CHEMBL5169599
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL5169599 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | CXFSVKGROITHRY-GXTWGEPZSA-N |
2
Targets
2
Activities
2
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
264.8
MW (Da)
3.24
ALogP
3
HBA
2
HBD
56.0
PSA (Ų)
0.86
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 9.3
Ki 1 meas. best 8.7
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Rattus norvegicus CHEMBL376 | EC50 | 9.3 | 9.3 | 0.5 | 1 |
| Androgen receptor CHEMBL3056 | Ki | 8.7 | 8.7 | 2.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Rattus norvegicus | EC50 | = | 0.5 | nM | 9.3 | Effect of compound in muscle of orchidectomy (ORX) rat model | 35786895 |
| Androgen receptor | Ki | = | 2.0 | nM | 8.7 | Agonist activity at Androgen receptor expressed in mouse C2C12 cells | 35786895 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 35786895 | 10.1021/acs.jmedchem.2c00716 | Androgen receptor | 1 |
| 35786895 | 10.1021/acs.jmedchem.2c00716 | Rattus norvegicus | 1 |
Data from ChEMBL 36 via Core Engine