Compound Detail
CHEMBL5185120
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
CCCC[C@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@]1(C)CCC/C=C\CCC[C@](C)(NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2ccccc2)NC(=O)CCNC(C)=O)C(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1)C(=O)N[C@@H](CC(C)C)C(N)=O
Basic Information
| ChEMBL ID | CHEMBL5185120 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | VHDGASVCGHLVRW-ZQJHWFDXSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
5
Publications
0
Known Names
Molecular Properties
2014.5
MW (Da)
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Kd 1 meas. best 6.02
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| dsDNA CHEMBL3832741 | Kd | 6.02 | 6.02 | 947.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| dsDNA | Kd | = | 947.0 | nM | 6.02 | Binding affinity to FITC-labelled dsDNA (unknown origin) assessed as dissociatio... | 35647551 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 35647551 | 10.1039/d1md00371b | DNA | 2 |
| 35647551 | 10.1039/d1md00371b | dsDNA | 1 |
| 35647551 | 10.1039/d1md00371b | Erythrocyte | 1 |
| 35647551 | 10.1039/d1md00371b | Cell membrane | 1 |
| 35647551 | 10.1039/d1md00371b | Pseudomonas aeruginosa | 1 |
Data from ChEMBL 36 via Core Engine