Compound Detail
CHEMBL519277
KUSHENOL P Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
C=C(C)C(CCC(C)(C)O)Cc1c(O)cc(O)c2c1O[C@H](c1ccc(O)cc1OC)CC2=O
Basic Information
| ChEMBL ID | CHEMBL519277 |
| Name | KUSHENOL P |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | XOPDZJVJVVORSL-GMTBNIFVSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
456.5
MW (Da)
4.80
ALogP
7
HBA
4
HBD
116.5
PSA (Ų)
0.42
QED
0
Ro5 Violations
8
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.69
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| RAW264.7 CHEMBL612557 | IC50 | 4.69 | 4.69 | 20400.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| RAW264.7 | IC50 | = | 20400.0 | nM | 4.69 | Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-... | 26073007 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 10654410 | 10.1021/np990051d | Unchecked | 6 |
| 26073007 | 10.1016/j.bmcl.2015.05.062 | RAW264.7 | 2 |
Data from ChEMBL 36 via Core Engine