Compound Detail
CHEMBL5196337
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL5196337 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | NHOBWBSMNFECBL-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
399.4
MW (Da)
4.84
ALogP
5
HBA
1
HBD
77.2
PSA (Ų)
0.52
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.43
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Solute carrier family 22 member 12 CHEMBL6120 | IC50 | 5.43 | 5.43 | 3670.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Solute carrier family 22 member 12 | IC50 | = | 3670.0 | nM | 5.43 | Inhibition of human URAT1 mediated 14C-uric acid uptake expressed in HEK293 cell... | 35084182 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 35084182 | 10.1021/acs.jmedchem.1c02057 | Mus musculus | 2 |
| 35084182 | 10.1021/acs.jmedchem.1c02057 | Solute carrier family 22 member 12 | 1 |
Data from ChEMBL 36 via Core Engine