Compound Detail
CHEMBL5196942
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Basic Information
| ChEMBL ID | CHEMBL5196942 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | HPMJGRNXLORLHD-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
392.5
MW (Da)
2.86
ALogP
7
HBA
1
HBD
82.6
PSA (Ų)
0.42
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 7.4
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| RPMI 8402 CHEMBL612517 | IC50 | 7.4 | 7.4 | 40.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| RPMI 8402 | IC50 | = | 40.0 | nM | 7.4 | Cytotoxicity against human RPMI 8402 cells assessed as cell growth inhibition me... | 35413618 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 35413618 | 10.1016/j.ejmech.2022.114304 | RPMI 8402 | 1 |
Data from ChEMBL 36 via Core Engine