Compound Detail
CHEMBL5205503
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Basic Information
| ChEMBL ID | CHEMBL5205503 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | PVIGNGPOZZVVTQ-PFONDFGASA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
350.5
MW (Da)
4.68
ALogP
3
HBA
1
HBD
81.4
PSA (Ų)
0.25
QED
0
Ro5 Violations
16
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.46
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Palmitoyltransferase ZDHHC20 CHEMBL5169156 | IC50 | 5.46 | 5.46 | 3450.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Palmitoyltransferase ZDHHC20 | IC50 | = | 3450.0 | nM | 5.46 | Inhibition of human myc-His6-tagged zDHHC20 expressed in HEK293T cells using 5-F... | 36262404 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 36262404 | 10.1021/acsmedchemlett.2c00336 | Palmitoyltransferase ZDHHC20 | 1 |
Data from ChEMBL 36 via Core Engine