Compound Detail
CHEMBL521960
INUVISCOLIDE Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL521960 |
| Name | INUVISCOLIDE |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | GTYUWNQOOLJZBM-XLFUENPSSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
248.3
MW (Da)
2.21
ALogP
3
HBA
1
HBD
46.5
PSA (Ų)
0.41
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 5.02
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| RAW264.7 CHEMBL612557 | IC50 | 5.02 | 4.84 | 9640.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| RAW264.7 | IC50 | = | 9640.0 | nM | 5.02 | Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-... | 21924800 |
| RAW264.7 | IC50 | = | 21900.0 | nM | 4.66 | Antiinflammatory action in mouse RAW264.7 cells assessed as inhibition of LPS-in... | 21894898 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1016/j.bse.2012.02.012 | Myzus persicae | 7 |
| 10217718 | 10.1021/np980132u | Mus musculus | 2 |
| 21894898 | 10.1021/np200319x | RAW264.7 | 2 |
| 21924800 | 10.1016/j.ejmech.2011.08.047 | RAW264.7 | 2 |
Data from ChEMBL 36 via Core Engine