Compound Detail
CHEMBL5219751
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Basic Information
| ChEMBL ID | CHEMBL5219751 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | JZMTYFZDRIYFTR-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
356.8
MW (Da)
2.06
ALogP
6
HBA
2
HBD
98.7
PSA (Ų)
0.70
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.73
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Adenylate cyclase type 10 CHEMBL5854 | IC50 | 5.73 | 5.73 | 1876.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Adenylate cyclase type 10 | IC50 | = | 1876.0 | nM | 5.73 | Inhibition of human ADCY10 assessed as cAMP accumulation preincubated for 15 min... | 36346696 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 36346696 | 10.1021/acs.jmedchem.2c01133 | Adenylate cyclase type 10 | 1 |
Data from ChEMBL 36 via Core Engine